Some shows you may have missed because 1. The network Gods deigned them unpopular and pulled them off the air too soon; 2. The audience didn't give them enough support and the network Gods cancelled them or 3. They were too smart for the new demographic: Dimwits who prefer to watch obese people work out and be yelled at, losers living in an apartment together "hook up" or single men/women act like idiots to get a rose and maybe "find love" than to actually have to pay attention to dialogue, story lines and character development. But I'm not bitter.
I knew from the first episode that I would like "Freaks and Geeks". This show made me uncomfortable while making me laugh. It is a coming-of-age comedy/drama about teenagers in the 80s, living in Michigan and it is incredibly real in it's portrayal of both the times and what life can be like as teens, tweens and in-betweens. The show was hilarious, painful to watch and thought-provoking all at the same time, and featured a cast of unknowns (including a certain failed Oscar host, James Franco, and others you will recognize from recent roles.) who were perfect in their roles. A great, great show. My review here is short, I am needed back at my job. Look it up on imdb, then rent or stream it. I think you'll enjoy yourself.
So add to my list-- what shows did you love that bit the dust? Why do you think it is that so many great shows get cancelled? Am I being too hard on the watchers of "reality" TV? Is there intelligent life out there?